Abstract: In order to efficiently recover a refractory lead-zinc oxide ore from Sichuan，aiming at the problems of high mud content，high oxidation rate，iron oxide mineral seriously impregnated with leadzinc ore，brittle dolomite and high calcite content，under the conditions of lead content of 3.18%，zinc con⁃ tent of 5.49%，lead oxidation rate of 38.36% and zinc oxidation rate of 73.95%，the technological process of first selecting sulfide and oxide lead minerals，then selecting zinc sulfide minerals and finally selecting zinc oxide minerals was adopted. Good beneficiation indexes of lead concentrate with lead grade of 45.36% and lead recovery rate of 85.33%，zinc concentrate with total zinc grade of 40.42% and total recovery rate of 86.28% were obtained.

Key words: oxysulfide mixed lead-zinc ore, efficient separation, recovery rate