Abstract: The research status of organic depressor for sulfide ore flotation was summarized in this paper. The organic depressor for sulfide ore flotation includes macromolecular depressor and micromolecule depressor, the nature of which was closely related to its structure separately. Research on molecule design of organic depressor molecular for sulfide ore through the structure performance criterion and computer-aided molecular design (CAMD) technology can not only purposely and fast design reagents, but also save development cost. Preliminarily relationship estimate on structure-property-environment using CAMD technology can reduce chemical reagents contamination from the origin as far as possible, realize green synthesis for depressor.

Key words: Organic depressor, Flotation, Sulfide ore, Computer-aided molecular design, Molecular structure