Abstract: In order to meet the production demand of acid-grade fluorite powder in a kaolin-type flu⁃ orite mine in Henan Province，a systematic beneficiation process test is carried out to solve the problem of serious mud cover caused by easily mudded gangue such as kaolin and talc and calcium-containing gangue such as calcite in the ore，and the floatability of minerals is similar，which is difficult to achieve efficient separation of fluorite and gangue minerals. Through detailed condition tests，the flotation reagent system with collector sodium oleate（500 g/t），high-efficiency inhibitor SY-20（1 000 g/t）and organic polymer regulator TZ-01（500 g/t）as the core is determined.The fluorite concentrate with CaF2 grade of 97.14% and recovery of 84.62% is obtained by adopting the closed-circuit process of one roughing，two scavenging and seven cleaning.The product index fully meets the quality requirements of acid-grade fluorite powder， which solves the separation problem of refractory fluorite ore with high mud content and high gangue con⁃ tent，and provides a reliable technical path.

Key words: fluorite, kaolin, flotation, adjustment agent, inhibitor