Abstract: In order to provide theoretical and technical basis for heavy metal waste slag or contaminat⁃ ed soil stabilization remediation by using industrial and agricultural solid waste，the synchronous stabiliza⁃ tion effect of industrial solid waste steel slag and desulfurization gypsum，agricultural solid waste bagasse and chicken manure on heavy metals in metallurgical waste residue was studied. Under the conditions of the mixing ratio（volume ratio）of solid waste and waste slag in the reaction layer was 1∶9，and the ratio of material desulfurization gypsum，steel slag，bagasse，poultry manure was 1∶1∶6∶12，the change of leach⁃ ing toxicity on As，Pb and Zn in the waste slag by 360 days was tested. At the same time，the microbial com⁃ munity of the reaction layer was analyzed for 360 days under the condition of metallurgy-agriculture solid waste synergy. The results showed that the leaching toxicity of As，Pb and Zn was respectively reduced by 99.8%，100%（NG）and 86.5%，and the leaching water was reached the surface water quality standard of Class III. From the microbial community data of 180 d and 360 d，the proportion of shared OTU were gradu⁃ ally decreased by 22.3 percentage points and 11.8 percentage points respectively.The high-abundance spe⁃ cies were relatively stable at phylum and class level in 180 d and 360 d，in which class as Gammaproteobac⁃ teria，Alphaproteobacteria，Actinobacteria，Bacteroidia，Fourth phylum chloroflexia，Bacilli，Gemmatimonade⁃ tes are higher than others，so it is considered that the multi-layer covering mainly induces changes in the abundance of the above flora，which in turn affects the morphology and toxicity of heavy metals.

Key words: metallurgical solid waste, agriculture solid waste, heavy metal, stabilization, microorgan? isms