Abstract: Based on the mineral properties of a cyanide tailings in Xinjiang, test on choice and dosage of agent like inhibitor, activating agent, collector, etc in prior separation flotation of copper and zinc, opencircuit whole process and closedcircuit test were done. The result indicated: one roughing, one scavenging, three reconcentrate, priority in turn flotation technology of copper and zinc of middling sequence recurrence, could better recovered copper, zinc and quantities of gold and silver. Copper concentrate with copper grade 16.88% and recovery rate 79.70%,gold recovery rate 34.97%,silver recovery rate 33.07% and zinc concentrate with zinc grade 52.07% and recovery rate 63.77% were obtained, twice recovery of mineral resources were realized.

Key words: Cyanide tailing, Collector, Inhibitor