Abstract: With the continuous mining of underground metal mines，the network of tunnel engineer⁃ ing is becoming increasingly complex，and ventilation problems are becoming more prominent. An under⁃ ground metal mine in Anhui Province adopts the sublevel open stoping and subsequent filling mining meth⁃ od，which has the characteristics of multi-level mining. Based on the Ventsim，a numerical model of mine ventilation is established. Combined with field investigation and model analysis，the ventilation resistance in the upper mining area of -190 m is large and the inlet air is polluted. The air leakage in the -240 m middle mining area leads to insufficient air volume in the western mining area. The return air in the west⁃ ern mining area of the - 290 m section is not smooth. In view of the above problems，an optimization scheme of zoning regulation and air leakage control is proposed. Installing auxiliary fans are installed in the upper mining area of - 190 m to reduce ventilation resistance. Plugging the air leakage channel is plugged in the middle section of -240 m and -290 m，and the auxiliary fan is installed in the -290 m to assist the return air.Verified by the ventilation network solution，the optimized air volume of each section is balanced，and the wind speed meets the safety regulations，which effectively solves the problem of air flow regulation.This study can provide reference for the optimization and control of ventilation system in the same type of mine.

Key words: mine ventilation system, air leakage control, ventilation network settlement, system opti? mization