Abstract: The lead grade of a lead-zinc oxide ore in Yunnan is 1.67%，the zinc grade is 9.21%，and the zinc oxidation rate is 55.81%. In order to improve the recovery rate of lead-zinc oxide ore and avoid the waste of ore resources，aiming at the problems of various elements，high oxidation rate and difficult flotation of lead-zinc oxide ore at the present stage，experimental studies on grinding fineness，reagent system and flotation process are carried out.The test results show that the mixed flotation of zinc sulfide and zinc oxide is beneficial to shorten the flotation process. Under the optimal test conditions，the closed-circuit test obtains lead concentrate with lead grade of 39.25%，zinc content of 13.54%，lead recovery rate of 59.90% and zinc concentrate with zinc grade of 50.24%，lead content of 2.13%，zinc recovery rate of 77.52%. The zinc recov‐ ery rate is improved and satisfactory test indicators are obtained.

Key words: ore diversification, mixed flotation, process shortening, recovery rate