Abstract: Abstract In order to solve the problem of efficient recovery of complex refractory gold ore in China， in view of the current situation that the existing separation technology is difficult to meet the current demand for efficient flotation of refractory gold ore，the research progress of pretreatment technology and new en⁃ hanced flotation technology of refractory gold ore is systematically sorted out by analyzing and studying the new high-efficiency and environmentally friendly separation technology and mechanism. The characteristics of the new technology are compared，the advantages and existing problems of each technology are expound⁃ ed. At the same time，it is pointed out that the research and development of efficient recovery technology for refractory gold mines in the future still needs to be strengthened，and the direction of technology research and development in the field of gold ore separation is prospected.

Key words: gold mine, flotation, pretreatment, nano-bubble