Abstract: In order to promote the efficient and clean utilization of molybdenum resources and solve the separation problem of complex copper-molybdenum ore，aiming at the problems of insufficient selectiv⁃ ity，large dosage，poor environmental protection，the development process of molybdenum reagents is sys⁃ tematically reviewed，and the structural characteristics and mechanism of new collectors，inhibitors and foaming agents are emphatically analyzed.The comparison between the new reagent and the traditional re⁃ agent is carried out from the aspects of flotation index，economic cost and environmental impact. Combined with typical industrial application examples，the practical efficiency of the new reagent is verified.The re⁃ sults show that the new molybdenum reagents generally have the characteristics of strong selectivity，low dosage and environmental friendliness，but there are still limitations in industrial applicability and cost control.In the future，molybdenum reagents should be developed in the four core directions of high efficien⁃ cy，green environmental protection，low cost generalization and“reagent-process”collaborative optimiza⁃ tion，so as to break through the technical bottleneck and improve the comprehensive recovery and utiliza⁃ tion rate of molybdenum resources.

Key words: new reagents for molybdenum selection, performance comparison, industrial application case