Abstract: To reduce the vibration caused by large-scale open-pit mining blasting and weaken the damage to the slope caused by blasting，a combined air-spacing explosive blasting method in the middle and bottom sections was adopted.Based on the actual conditions of the mine，the main parameters of the blasting test were determined，and the blasting design was carried out.A blasting hole structure was pro⁃ posed，which consisted of air columns，emulsion explosives，air columns，emulsion explosives，and fill⁃ ing materials in the order from bottom to top.The length of the air columns at the bottom and middle of the hole was 1 and 2.5 m respectively.Three groups of interval and coupled blasting tests were carried out to compare the blasting effects.The test results showed that the overall blasting effect of the coupled blasting was better.Due to the large height of the upper filling，there were more large blocks after blasting.During the air-spacing explosive blasting，the surrounding rocks would be subjected to the simultaneous action of the upper and lower explosive columns，generating two-directional shock waves that superimposed，effec⁃ tively reducing the rate of large blasting blocks，improving the energy utilization rate of the explosives，re⁃ ducing the blasting cost，and achieving a vibration reduction rate of 15.68%.This effectively weakened the damage of blasting vibration to the slope，providing a basis for subsequent safe and efficient blasting in the open-pit mining area.

Key words: slope, interval charging, blasting vibration